Members-only rates
4.8 / 5 Excellent

Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
Hampton Inn & Suites St. Louis/South I-55 – St. Louis, MO
Hampton Inn & Suites St. Louis/South I-55 – St. Louis, MO
Check in 3:00 PM
Check out 11:00 AM

About Hampton Inn & Suites St. Louis/South I-55

The Hampton Inn & Suites - Saint Louis South Interstate 55 is directly off Interstate 55, and 15 mi south of downtown St. Louis and its famous arch. Rooms at Hampton Inn & Suites - Saint Louis South Interstate 55 have flat-screen TVs. All rooms come furnished with a microwave, refrigerator, and work desk. A breakfast buffet is served every morning and newspapers are delivered to rooms at the Hampton Inn & Suites - Saint Louis South Interstate 55. Guests can relax in the indoor pool and spa bath after a long day or a workout in the hotel’s fitness center. The hotel offers many convenient amenities, such as a business center, an ATM/cash machine, and dry cleaning. The St. Louis Zoo is 30 minutes away from the Saint Louis South Interstate 55 Hampton Inn & Suites. The hotel is 25 mi away from Cahokia Mounds State Park, a UNESCO World Heritage site that features the largest pre-Columbian city in North America. One of the largest breweries in the world, the Anheuser-Busch Brewery, is 20 mi away.

Amenities

  • 24-hour front desk
  • Meeting space
  • Fitness center
  • On-site dining
  • Café / coffee shop
  • Business center
  • Express check-in / check-out
  • Concierge
  • Dry cleaning
  • Self-service laundry
  • Luggage storage
  • Full kitchen / kitchenette
  • In-room refrigerator
  • Pool
  • Spa / sauna
  • Pet friendly
  • Family friendly
  • Wheelchair accessible
  • Smoke-free property
  • Air conditioning
  • Elevator
  • In-room safe

Reviews

4.8 / 5
Excellent 1007 reviews
  • Engine customer Aug 2026

    Very clean, safe, and comfortable!

  • Engine customer Aug 2026

    Exceptional

  • Engine customer Aug 2026

    Exceptional

  • Engine customer Aug 2026

    It was a comfortable stay and breakfast was great!

  • Engine customer Aug 2026

    The room was very spacious and had a separate sitting area. It was also very clean. Nothing

  • Engine customer Aug 2026

    Clean room, good breakfast and perfect location for out stay. Interstate was conveniently close. 2nd time staying those year and a solid choice both times

  • Engine customer Aug 2026

    Superb

  • Engine customer Aug 2026

    Great place clean rooms

  • Engine customer Aug 2026

    Everything. Nothing

  • Engine customer Aug 2026

    Great staff, very clean room and building.

  • Engine customer Aug 2026

    Everything was fine

  • Engine customer Aug 2026

    The only thing I would change was the pillow situation! The pillows hardly gave any support and we were unable to get extra.

  • Engine customer Aug 2026

    Nothin to report

  • Engine customer Aug 2026

    Staff was very friendly and helpful. Nice breakfast and entire property was clean. na

  • Engine customer Jul 2026

    A big shout out to Priscilla and crew for her professionalism , warm and welcoming personality and kindness !!!

  • Engine customer Jul 2026

    Room was clean and breakfast was excellent. But bed was older and squeezing and pillows need to be replaced and the A/C only went to 68 would be the only negative.

  • Engine customer Jul 2026

    The hotel was comfortable and staff was friendly. The reservation was not found easily due to being hotel.com. Probably won't use that service again.

  • Engine customer Jul 2026

    The hotel is very beautiful and modern. Our room was excellent! The beds are very comfortable, but most importantly the front desk staff are some of the most amazing and helpful people! And I would love to give a shout out to Priscilla, who was just very accommodating and very nice!! Bonus : the food is good !!

  • Engine customer Jul 2026

    Friendly staff, quiet, clean,safe, easy parking. Excellent breakfast. Would definitely stay there again.

  • Engine customer Jul 2026

    Excellent stay all around. Breakfast was on point

Frequently asked questions about Hampton Inn & Suites St. Louis/South I-55

Does Hampton Inn & Suites St. Louis/South I-55 have free Wi-Fi?
Yes, Hampton Inn & Suites St. Louis/South I-55 offers free Wi-Fi for all guests. Free wired internet is also available in select rooms.
Does Hampton Inn & Suites St. Louis/South I-55 offer parking?
Yes, Hampton Inn & Suites St. Louis/South I-55 offers free parking on-site.
Does Hampton Inn & Suites St. Louis/South I-55 have meeting spaces, conference centers, or conference rooms?
Yes. Hampton Inn & Suites St. Louis/South I-55 features meeting spaces and dedicated conference rooms, suitable for corporate meetings and group gatherings. Banquet and reception facilities are also available.
Does Hampton Inn & Suites St. Louis/South I-55 have a fitness center?
Yes, Hampton Inn & Suites St. Louis/South I-55 features an on-site fitness center for guests. Additional wellness amenities include spa, pool.
Where is Hampton Inn & Suites St. Louis/South I-55 located, and how walkable is the area?
Hampton Inn & Suites St. Louis/South I-55 is located at 4200 Midamerica Lane, St. Louis, MO 63129. With a Walk Score of 44, the area is rated Car-Dependent. A car or rideshare is recommended for most trips in this area.

Why no public rates?

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